Peter Mancuso Selected Research

Prostaglandins

1/2016	Increased lethality and defective pulmonary clearance of Streptococcus pneumoniae in microsomal prostaglandin E synthase-1-knockout mice.
5/2012	E-prostanoid 2 receptor signaling suppresses lung innate immunity against Streptococcus pneumoniae.
8/2009	E-prostanoid 3 receptor deletion improves pulmonary host defense and protects mice from death in severe Streptococcus pneumoniae infection.

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Peter Mancuso Research Topics

Disease

12	Infections 01/2022 - 08/2009
10	Pneumococcal Pneumonia 01/2018 - 01/2006
9	Inflammation (Inflammations) 01/2019 - 08/2009
8	Obesity 01/2022 - 04/2013
7	Pneumonia (Pneumonitis) 01/2022 - 04/2002
4	Starvation 01/2018 - 04/2002
4	Bacterial Pneumonia 01/2016 - 04/2002
3	Cardiovascular Diseases (Cardiovascular Disease) 01/2021 - 07/2010
3	Insulin Resistance 01/2021 - 03/2013
3	Knee Osteoarthritis 04/2016 - 06/2013
3	Bacterial Infections (Bacterial Infection) 01/2016 - 08/2009
3	Chronic Obstructive Pulmonary Disease (COPD) 07/2015 - 02/2013
3	Asthma (Bronchial Asthma) 01/2015 - 01/2005
3	Pneumococcal Infections 05/2012 - 08/2009
2	Respiratory Tract Infections (Respiratory Tract Infection) 01/2018 - 08/2013
2	Malnutrition (Nutritional Deficiencies) 01/2005 - 04/2002
1	Diabetes Mellitus 01/2021
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2021
1	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2020
1	Major Depressive Disorder (Major Depressive Disorders) 11/2018
1	Overweight 01/2017
1	Pain (Aches) 04/2016
1	Communicable Diseases (Infectious Diseases) 05/2015
1	Metabolic Diseases (Metabolic Disease) 05/2015
1	Mood Disorders (Mood Disorder) 10/2014
1	Synovitis 05/2014
1	Osteophyte 05/2014
1	Osteoarthritis 05/2014
1	Lung Injury 02/2014
1	Morbid Obesity 01/2014
1	Hyperglycemia 01/2014
1	Hot Flashes 09/2013
1	Virus Diseases (Viral Diseases) 01/2013
1	Status Asthmaticus 03/2012
1	Hypertension (High Blood Pressure) 07/2010
1	Type 2 Diabetes Mellitus (MODY) 07/2010
1	Coronary Disease (Coronary Heart Disease) 07/2010
1	Ischemic Stroke 07/2010
1	Stroke (Strokes) 07/2010

Drug/Important Bio-Agent (IBA)

15	LeptinIBA 01/2021 - 04/2002
7	AdipokinesIBA 01/2021 - 01/2006
7	LipidsIBA 01/2019 - 01/2005
6	AdiponectinIBA 01/2021 - 07/2010
6	Hormones (Hormone)IBA 01/2019 - 01/2006
6	CytokinesIBA 01/2016 - 03/2010
6	LeukotrienesIBA 01/2015 - 04/2002
4	Leptin ReceptorsIBA 01/2018 - 06/2008
3	Dinoprostone (PGE2)FDA Link 01/2016 - 01/2013
3	ProstaglandinsIBA 01/2016 - 08/2009
3	SmokeIBA 02/2014 - 03/2010
3	Prostaglandins EIBA 07/2012 - 08/2009
2	Interleukin-6 (Interleukin 6)IBA 01/2022 - 03/2010
2	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 07/2010
2	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 01/2020 - 10/2014
2	Interleukin-13IBA 01/2018 - 07/2014
2	C-Reactive ProteinIBA 04/2016 - 07/2010
2	Triglycerides (Triacylglycerol)IBA 01/2016 - 01/2014
2	Biomarkers (Surrogate Marker)IBA 05/2015 - 07/2010
2	cysteinyl-leukotrieneIBA 01/2015 - 01/2011
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 07/2014 - 03/2010
2	bisphenol AIBA 07/2014 - 04/2013
1	Interleukin-17 (Interleukin 17)IBA 01/2022
1	Proteins (Proteins, Gene)FDA Link 01/2021
1	Fatty Acids (Saturated Fatty Acids)IBA 01/2020
1	OzoneIBA 01/2017
1	Prostaglandin-E SynthasesIBA 01/2016
1	EnzymesIBA 01/2016
1	Suppressor of Cytokine Signaling 3 ProteinIBA 01/2016
1	Adrenal Cortex Hormones (Corticosteroids)IBA 07/2015
1	GlucocorticoidsIBA 07/2015
1	Fluticasone (Cutivate)FDA LinkGeneric 07/2015
1	Suppressor of Cytokine Signaling ProteinsIBA 05/2015
1	InterleukinsIBA 07/2014
1	Epoxy Compounds (Epoxides)IBA 07/2014
1	Histamine (Histamine Dihydrochloride)FDA Link 07/2014
1	polycarbonateIBA 07/2014
1	Prostaglandin D2IBA 07/2014
1	OvalbuminIBA 01/2014
1	Forkhead Transcription Factors (Forkhead Box Proteins)IBA 02/2013
1	Interleukin-8 (Interleukin 8)IBA 02/2013
1	2- (4- morpholinyl)- 8- phenyl- 4H- 1- benzopyran- 4- oneIBA 02/2013
1	Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA 02/2013
1	QuercetinIBA 02/2013
1	ChemokinesIBA 02/2013
1	Pancreatic Elastase (Elastase)IBA 02/2013
1	Erlotinib Hydrochloride (CP 358,774)FDA Link 02/2013
1	Tyrosine (L-Tyrosine)FDA Link 07/2012
1	Interleukin-12 (IL 12)IBA 05/2012
1	lipoxin A4IBA 03/2012
1	8-epi-prostaglandin F2alphaIBA 03/2012
1	LipoxinsIBA 03/2012
1	Phospholipases (Phospholipase)IBA 01/2011
1	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 07/2010
1	ORALIT (ORS)IBA 07/2010
1	Insulin (Novolin)FDA Link 07/2010
1	HDL CholesterolIBA 07/2010
1	LDL CholesterolIBA 07/2010
1	AerosolsIBA 05/2010

Therapy/Procedure

1	Therapeutics 07/2015
1	Airway Management 01/2015